Our Hotel

University of Chicago Hotel

At Hyatt Place Chicago – South University Medical Center, we offer a high-tech business environment with warm, casual surroundings. Our fresh, contemporary hotel near the University of Chicago offers modern, roomy rooms with plush Hyatt Grand Beds®, Cozy Corner Sofa Sleeper, state-of-the-art media and work centers, and swiveling 42" flat screen HDTV with a Hyatt Plug Panel™ for electronics. Wake up to our free a.m. Kitchen Skillet™ breakfast served daily in the Gallery Kitchen.

Hyatt Place Chicago-South/University Medical Center is just 13.9 miles from Midway Airport and 23.5 miles from Chicago O’Hare Airport. For ease of travel, our hotel provides a complimentary shuttle service to the University of Chicago and Medical Center campuses, as well as local attractions within Hyde Park. If you’re driving to our University of Chicago hotel, we offer convenient valet parking.The hotel offers a 15% off the best available rate for friends and family of the University of Chicago, based on availability. Please use this link to book and check availability.


Hotel Features

  • Complimentary hotel-wide Wi-Fi Internet access
  • Gallery Menu, Fresh 24/7 with mouthwatering options including our signature flatbreads & more 
  • Enjoy your complimentary a.m. Kitchen Skillet™ served daily, with hot breakfast items, fresh fruit, oatmeal and plenty more to choose from.
  • Grab 'n Go case offers new sandwiches & greens from our Gallery Menu and bottled beverages for moments on the run
  • Valet Parking, $37/ night with in and out privileges.
  • Relaxing Coffee to Cocktails Bar serves Starbucks® specialty coffees & teas, premium beers, wines & cocktails
  • This is a smoke free environment. Visitors will be charged $200 if you smoke in the rooms.
  • Self-service check-in/check-out kiosks
  • Audio visual equipment
  • Complimentary 24-hour Stay Fit® fitness center with Life Fitness® cardio equipment
More Hotel Features >>

Maps and Directions

Chicago Midway International Airport (MDW): 14 miles miles from the hotel
Head north on Cicero Avenue for 1¾ miles to I-55 N/S the Stevenson Expressway. Then turn right to merge onto I-55 N and continue for seven miles. Keep right at the fork and follow signs for U.S.-41 S/Lake Shore Drive. S and merge onto U.S. 41 S/S Lake Shore Drive, continuing for four miles. Exit onto 53rd Street, continuing for ½ mile. Then turn right onto S. Harper Avenue.

Chicago O’Hare International Airport (ORD): 23½ miles from the hotel
Head south on North East River Road toward North Chester Avenue. Turn left onto IL-171 N/N  Cumberland Avenue, continuing for 1½ miles. Take the ramp onto I-90 E continuing for 14¾ miles. Take exit 53 to merge onto I-55 N toward Lake Shore Drive, continuing 2¼ miles. Keep right at the fork, follow signs for U.S.-41 S/Lake Shore Dr. S and merge onto U.S. 41 S/S Lake Shore Dr., continuing for 4 miles. Exit onto 53rd Street, continuing for ½ mile. Turn right onto S. Harper Avenue.

More Maps and Directions >>


We are partnered with the business, Windy City Limos,
for all transportation needs to O'hare Airport (ORD) and Chicago Midway Airport.


Once you are here, feel free to utilize our free shuttle service to the University of Chicago, Medical Center and Hyde Park. Please note that this service is only available on request and between 7am-7pm.

More Transportation >>

Pet Policy

For guest staying 1-6 nights, a $75 non-refundable pet fee will be administered. Guests staying 7-30 nights, a $75 non-refundable pet fee plus an additional $100 cleaning fee will be administered. Guests stay 30 + nights, please contact the hotel. The fee(s) will be inclusive of taxes. A maximum of 2 dogs per room are permitted. Only dogs weighing 50 lbs and under are permitted; two dogs may be allowed in a guestroom provided the combined weight of both dogs does not exceed 75 pounds; the pet fee encompasses this and pets exceeding are at the hotels discretion. All pets must be housebroken.

More Pet Policy >>
Make a Reservation

  Please enter date in mmm/dd/yyyy format

  • Rooms
  • Adults
  • Children help
Age of Children
(at time of stay)
Please complete the mandatory fields.
 Special Rates (AAA, GOVT, ...)
  • Select a Special Ratehelp

Check-in Time: 3:00 p.m.
Check-out Time: 12:00 p.m.

5225 S. Harper Avenue, Chicago, Illinois, USA, 60615

  • Tel: +1 773 752 5300